Inflammation and Immune Response

  1. Chronic Inflammation
    1. Characteristics and Definition
      1. Duration and Persistence
        1. Cellular Composition
          1. Tissue Architecture Changes
          2. Causes and Triggers
            1. Persistent Infections
              1. Mycobacterial Infections
                1. Viral Infections
                  1. Fungal Infections
                    1. Parasitic Infections
                    2. Autoimmune Diseases
                      1. Rheumatoid Arthritis
                        1. Inflammatory Bowel Disease
                          1. Multiple Sclerosis
                          2. Prolonged Exposure to Irritants
                            1. Environmental Toxins
                              1. Particulate Matter
                                1. Chemical Agents
                                2. Metabolic Factors
                                  1. Diabetes-Associated Inflammation
                                3. Cellular Components
                                  1. Macrophages in Chronic Inflammation
                                    1. Activated Macrophage Phenotypes
                                      1. Epithelioid Cells
                                        1. Multinucleated Giant Cells
                                          1. Langhans Giant Cells
                                            1. Foreign Body Giant Cells
                                          2. Lymphocytes
                                            1. T Cell Subsets
                                              1. B Cells and Plasma Cells
                                              2. Other Cell Types
                                                1. Fibroblasts
                                                  1. Endothelial Cells
                                                    1. Tissue-Specific Cells
                                                  2. Granulomatous Inflammation
                                                    1. Granuloma Structure
                                                      1. Central Necrosis
                                                        1. Epithelioid Cells
                                                          1. Giant Cells
                                                            1. Lymphocyte Cuff
                                                            2. Types of Granulomas
                                                              1. Epithelioid Granulomas
                                                                1. Foreign Body Granulomas
                                                                2. Diseases with Granulomatous Inflammation
                                                                  1. Tuberculosis
                                                                    1. Sarcoidosis
                                                                      1. Crohn's Disease
                                                                        1. Hypersensitivity Pneumonitis
                                                                      2. Tissue Damage and Remodeling
                                                                        1. Matrix Metalloproteinases
                                                                          1. Tissue Destruction Mechanisms
                                                                            1. Fibrosis Development
                                                                              1. Organ Dysfunction

                                                                            Previous

                                                                            8. Resolution and Outcomes of Acute Inflammation

                                                                            Go to top

                                                                            Next

                                                                            10. Tissue Repair and Regeneration