Resolution and Outcomes of Acute Inflammation

Elimination of Inflammatory Stimulus

Clearance of Inflammatory Mediators

Neutrophil Apoptosis

Macrophage-Mediated Clearance

Restoration of Tissue Homeostasis

Vascular Normalization

Lipoxin Biosynthesis and Actions

Resolvin Classes

Protectin Functions

Maresin Activities

Scar Formation Process

Collagen Synthesis and Deposition

Fibroblast Activation

Angiogenesis

Tissue Remodeling

Wound Contraction

Failure of Resolution Mechanisms

Persistent Inflammatory Stimuli

Defective Apoptosis

Impaired Clearance

Transition Mechanisms