Neurology

  1. Neuro-oncology
    1. General Principles
      1. Classification of Brain Tumors
        1. WHO Classification
          1. Primary vs. Metastatic
            1. Benign vs. Malignant
            2. Epidemiology
              1. Incidence and Prevalence
                1. Age Distribution
                  1. Geographic Variations
                  2. Risk Factors
                    1. Genetic Syndromes
                      1. Environmental Factors
                        1. Previous Radiation
                        2. Pathophysiology
                          1. Tumor Growth
                            1. Mass Effect
                              1. Peritumoral Edema
                                1. Increased Intracranial Pressure
                              2. Primary Brain Tumors
                                1. Gliomas
                                  1. Astrocytomas
                                    1. Pilocytic Astrocytoma
                                      1. Pathology
                                        1. Clinical Features
                                          1. Imaging
                                            1. Management
                                            2. Diffuse Astrocytoma
                                              1. IDH-Mutant
                                                1. IDH-Wildtype
                                                  1. Pathology
                                                    1. Clinical Features
                                                      1. Management
                                                      2. Anaplastic Astrocytoma
                                                        1. Pathology
                                                          1. Clinical Features
                                                            1. Management
                                                            2. Glioblastoma
                                                              1. Pathology
                                                                1. Molecular Markers
                                                                  1. MGMT Methylation
                                                                    1. IDH Status
                                                                      1. 1p/19q Codeletion
                                                                      2. Clinical Features
                                                                        1. Imaging
                                                                          1. Management
                                                                            1. Surgery
                                                                              1. Radiation Therapy
                                                                                1. Chemotherapy
                                                                                  1. Targeted Therapy
                                                                                  2. Prognosis
                                                                                2. Oligodendrogliomas
                                                                                  1. Oligodendroglioma
                                                                                    1. Anaplastic Oligodendroglioma
                                                                                      1. Molecular Features
                                                                                        1. Clinical Features
                                                                                          1. Management
                                                                                          2. Ependymomas
                                                                                            1. Classification
                                                                                              1. Clinical Features
                                                                                                1. Management
                                                                                                2. Mixed Gliomas
                                                                                                  1. Oligoastrocytoma
                                                                                                    1. Clinical Features
                                                                                                      1. Management
                                                                                                    2. Meningiomas
                                                                                                      1. Classification
                                                                                                        1. WHO Grade I
                                                                                                          1. WHO Grade II
                                                                                                            1. WHO Grade III
                                                                                                            2. Location-Based Types
                                                                                                              1. Convexity Meningiomas
                                                                                                                1. Parasagittal Meningiomas
                                                                                                                  1. Sphenoid Wing Meningiomas
                                                                                                                    1. Posterior Fossa Meningiomas
                                                                                                                      1. Spinal Meningiomas
                                                                                                                      2. Clinical Features
                                                                                                                        1. Seizures
                                                                                                                          1. Focal Neurological Deficits
                                                                                                                            1. Headache
                                                                                                                              1. Cognitive Changes
                                                                                                                              2. Imaging
                                                                                                                                1. CT Findings
                                                                                                                                  1. MRI Findings
                                                                                                                                  2. Management
                                                                                                                                    1. Observation
                                                                                                                                      1. Surgical Resection
                                                                                                                                        1. Radiation Therapy
                                                                                                                                          1. Medical Management
                                                                                                                                        2. Pituitary Tumors
                                                                                                                                          1. Pituitary Adenomas
                                                                                                                                            1. Functional Adenomas
                                                                                                                                              1. Prolactinomas
                                                                                                                                                1. Growth Hormone-Secreting Adenomas
                                                                                                                                                  1. ACTH-Secreting Adenomas
                                                                                                                                                    1. TSH-Secreting Adenomas
                                                                                                                                                    2. Non-Functional Adenomas
                                                                                                                                                      1. Clinical Features
                                                                                                                                                        1. Hormonal Effects
                                                                                                                                                          1. Mass Effects
                                                                                                                                                          2. Diagnosis
                                                                                                                                                            1. Hormonal Testing
                                                                                                                                                              1. Imaging
                                                                                                                                                              2. Management
                                                                                                                                                                1. Medical Therapy
                                                                                                                                                                  1. Surgical Therapy
                                                                                                                                                                    1. Radiation Therapy
                                                                                                                                                                  2. Craniopharyngiomas
                                                                                                                                                                    1. Pathology
                                                                                                                                                                      1. Clinical Features
                                                                                                                                                                        1. Management
                                                                                                                                                                      2. Primary CNS Lymphoma
                                                                                                                                                                        1. Epidemiology
                                                                                                                                                                          1. Risk Factors
                                                                                                                                                                            1. Pathology
                                                                                                                                                                              1. Clinical Features
                                                                                                                                                                                1. Diagnosis
                                                                                                                                                                                  1. Management
                                                                                                                                                                                    1. Chemotherapy
                                                                                                                                                                                      1. Radiation Therapy
                                                                                                                                                                                        1. Stem Cell Transplantation
                                                                                                                                                                                      2. Medulloepitheliomas
                                                                                                                                                                                        1. Pathology
                                                                                                                                                                                          1. Clinical Features
                                                                                                                                                                                            1. Management
                                                                                                                                                                                            2. Pineal Region Tumors
                                                                                                                                                                                              1. Pineal Parenchymal Tumors
                                                                                                                                                                                                1. Germ Cell Tumors
                                                                                                                                                                                                  1. Clinical Features
                                                                                                                                                                                                    1. Management
                                                                                                                                                                                                    2. Choroid Plexus Tumors
                                                                                                                                                                                                      1. Choroid Plexus Papilloma
                                                                                                                                                                                                        1. Choroid Plexus Carcinoma
                                                                                                                                                                                                          1. Clinical Features
                                                                                                                                                                                                            1. Management
                                                                                                                                                                                                            2. Embryonal Tumors
                                                                                                                                                                                                              1. Medulloepithelioma
                                                                                                                                                                                                                1. Atypical Teratoid/Rhabdoid Tumor
                                                                                                                                                                                                                  1. Clinical Features
                                                                                                                                                                                                                    1. Management
                                                                                                                                                                                                                  2. Metastatic Brain Tumors
                                                                                                                                                                                                                    1. Epidemiology
                                                                                                                                                                                                                      1. Common Primary Sources
                                                                                                                                                                                                                        1. Lung Cancer
                                                                                                                                                                                                                          1. Breast Cancer
                                                                                                                                                                                                                            1. Melanoma
                                                                                                                                                                                                                              1. Renal Cell Carcinoma
                                                                                                                                                                                                                                1. Colorectal Cancer
                                                                                                                                                                                                                                2. Pathophysiology
                                                                                                                                                                                                                                  1. Hematogenous Spread
                                                                                                                                                                                                                                    1. Blood-Brain Barrier Disruption
                                                                                                                                                                                                                                      1. Tumor Microenvironment
                                                                                                                                                                                                                                      2. Clinical Features
                                                                                                                                                                                                                                        1. Symptoms
                                                                                                                                                                                                                                          1. Signs
                                                                                                                                                                                                                                            1. Presentation Patterns
                                                                                                                                                                                                                                            2. Diagnosis
                                                                                                                                                                                                                                              1. Neuroimaging
                                                                                                                                                                                                                                                1. Systemic Staging
                                                                                                                                                                                                                                                  1. Tissue Diagnosis
                                                                                                                                                                                                                                                  2. Management
                                                                                                                                                                                                                                                    1. Whole Brain Radiation Therapy
                                                                                                                                                                                                                                                      1. Stereotactic Radiosurgery
                                                                                                                                                                                                                                                        1. Surgical Resection
                                                                                                                                                                                                                                                          1. Systemic Therapy
                                                                                                                                                                                                                                                            1. Supportive Care
                                                                                                                                                                                                                                                            2. Prognosis
                                                                                                                                                                                                                                                              1. Prognostic Factors
                                                                                                                                                                                                                                                                1. Survival Outcomes
                                                                                                                                                                                                                                                              2. Leptomeningeal Metastases
                                                                                                                                                                                                                                                                1. Pathophysiology
                                                                                                                                                                                                                                                                  1. Clinical Features
                                                                                                                                                                                                                                                                    1. Diagnosis
                                                                                                                                                                                                                                                                      1. CSF Analysis
                                                                                                                                                                                                                                                                        1. Imaging
                                                                                                                                                                                                                                                                        2. Management
                                                                                                                                                                                                                                                                          1. Intrathecal Therapy
                                                                                                                                                                                                                                                                            1. Radiation Therapy
                                                                                                                                                                                                                                                                              1. Systemic Therapy
                                                                                                                                                                                                                                                                            2. Paraneoplastic Syndromes
                                                                                                                                                                                                                                                                              1. Pathophysiology
                                                                                                                                                                                                                                                                                1. Autoimmune Mechanisms
                                                                                                                                                                                                                                                                                  1. Onconeural Antibodies
                                                                                                                                                                                                                                                                                  2. Clinical Syndromes
                                                                                                                                                                                                                                                                                    1. Limbic Encephalitis
                                                                                                                                                                                                                                                                                      1. Cerebellar Degeneration
                                                                                                                                                                                                                                                                                        1. Opsoclonus-Myoclonus
                                                                                                                                                                                                                                                                                          1. Stiff-Person Syndrome
                                                                                                                                                                                                                                                                                            1. Lambert-Eaton Myasthenic Syndrome
                                                                                                                                                                                                                                                                                              1. Sensory Neuronopathy
                                                                                                                                                                                                                                                                                              2. Diagnosis
                                                                                                                                                                                                                                                                                                1. Clinical Criteria
                                                                                                                                                                                                                                                                                                  1. Antibody Testing
                                                                                                                                                                                                                                                                                                    1. Tumor Screening
                                                                                                                                                                                                                                                                                                    2. Management
                                                                                                                                                                                                                                                                                                      1. Tumor Treatment
                                                                                                                                                                                                                                                                                                        1. Immunosuppression
                                                                                                                                                                                                                                                                                                          1. Symptomatic Treatment
                                                                                                                                                                                                                                                                                                        2. Treatment Modalities
                                                                                                                                                                                                                                                                                                          1. Surgery
                                                                                                                                                                                                                                                                                                            1. Indications
                                                                                                                                                                                                                                                                                                              1. Surgical Techniques
                                                                                                                                                                                                                                                                                                                1. Craniotomy
                                                                                                                                                                                                                                                                                                                  1. Stereotactic Biopsy
                                                                                                                                                                                                                                                                                                                    1. Awake Craniotomy
                                                                                                                                                                                                                                                                                                                      1. Endoscopic Surgery
                                                                                                                                                                                                                                                                                                                      2. Intraoperative Monitoring
                                                                                                                                                                                                                                                                                                                        1. Complications
                                                                                                                                                                                                                                                                                                                        2. Radiation Therapy
                                                                                                                                                                                                                                                                                                                          1. External Beam Radiation
                                                                                                                                                                                                                                                                                                                            1. Stereotactic Radiosurgery
                                                                                                                                                                                                                                                                                                                              1. Brachytherapy
                                                                                                                                                                                                                                                                                                                                1. Proton Therapy
                                                                                                                                                                                                                                                                                                                                  1. Side Effects
                                                                                                                                                                                                                                                                                                                                  2. Chemotherapy
                                                                                                                                                                                                                                                                                                                                    1. Alkylating Agents
                                                                                                                                                                                                                                                                                                                                      1. Antimetabolites
                                                                                                                                                                                                                                                                                                                                        1. Topoisomerase Inhibitors
                                                                                                                                                                                                                                                                                                                                          1. Targeted Therapy
                                                                                                                                                                                                                                                                                                                                            1. Blood-Brain Barrier Considerations
                                                                                                                                                                                                                                                                                                                                            2. Immunotherapy
                                                                                                                                                                                                                                                                                                                                              1. Checkpoint Inhibitors
                                                                                                                                                                                                                                                                                                                                                1. CAR-T Cell Therapy
                                                                                                                                                                                                                                                                                                                                                  1. Vaccine Therapy
                                                                                                                                                                                                                                                                                                                                                  2. Supportive Care
                                                                                                                                                                                                                                                                                                                                                    1. Corticosteroids
                                                                                                                                                                                                                                                                                                                                                      1. Anticonvulsants
                                                                                                                                                                                                                                                                                                                                                        1. Venous Thromboembolism Prophylaxis
                                                                                                                                                                                                                                                                                                                                                          1. Symptom Management

                                                                                                                                                                                                                                                                                                                                                      Previous

                                                                                                                                                                                                                                                                                                                                                      10. Infections of the Nervous System

                                                                                                                                                                                                                                                                                                                                                      Go to top

                                                                                                                                                                                                                                                                                                                                                      Next

                                                                                                                                                                                                                                                                                                                                                      12. Disorders of the Peripheral Nervous System