Muscle Physiology

7.

Muscle Relaxation

7.1.

Cessation of Neural Stimulation

7.1.1.

Action Potential Termination

7.1.2.

Membrane Repolarization

7.2.

Calcium Removal

7.2.1.

Sarcoplasmic Reticulum Calcium Pumps

7.2.1.1.

7.2.1.2.

ATP Requirements

7.2.1.3.

Pump Regulation

7.2.2.

Calcium Sequestration

7.2.3.

Calsequestrin Binding

7.3.

Regulatory Protein Reset

7.3.1.

Calcium Dissociation from Troponin C

7.3.2.

Troponin Complex Return

7.3.3.

Tropomyosin Repositioning

7.3.4.

Actin Site Blocking

7.4.

Cross-bridge Detachment

7.4.1.

Loss of Myosin-Actin Interaction

7.4.2.

Return to Resting State

7.5.

Muscle Length Restoration

7.5.1.

7.5.2.

Passive Stretching Forces

7.5.3.

7.6.

Energy Requirements for Relaxation

7.6.1.

ATP for Calcium Pumping

7.6.2.

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8. Mechanics of Muscle Contraction