Iron Transport and Receptors in Bacteria

  1. Iron Acquisition and Bacterial Pathogenesis
    1. Nutritional Immunity Evasion
      1. Host Iron Sequestration Mechanisms
        1. Bacterial Countermeasures
          1. Evolutionary Arms Race
          2. Virulence Factor Functions
            1. Growth in Host Environments
              1. Tissue Invasion Capabilities
                1. Immune System Evasion
                  1. Biofilm Formation Enhancement
                  2. Pathogen-specific Systems
                    1. Uropathogenic E. coli
                      1. Multiple Siderophore Systems
                        1. Urinary Tract Colonization
                          1. Kidney Infection Mechanisms
                          2. Pseudomonas aeruginosa
                            1. Pyoverdine and Pyochelin
                              1. Lung Infection Models
                                1. Cystic Fibrosis Pathogenesis
                                2. Klebsiella pneumoniae
                                  1. Enterobactin and Aerobactin
                                    1. Pneumonia and Sepsis
                                      1. Hypervirulent Strains
                                      2. Mycobacterium tuberculosis
                                        1. Mycobactin and Carboxymycobactin
                                          1. Macrophage Survival
                                            1. Granuloma Formation
                                            2. Yersinia pestis
                                              1. Yersiniabactin System
                                                1. Plague Pathogenesis
                                                  1. Flea Vector Colonization

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                                              8. Iron Homeostasis Regulation

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                                              10. Therapeutic Applications and Drug Development