Iron Transport and Receptors in Bacteria

  1. Bacterial Iron Acquisition Strategies
    1. Siderophore-mediated Systems
      1. High-affinity Iron Chelation
        1. Secretion and Uptake Mechanisms
          1. Environmental Advantages
          2. Heme Acquisition Systems
            1. Heme Extraction from Host Proteins
              1. Specialized Transport Machinery
                1. Heme Degradation Pathways
                2. Ferrous Iron Transport
                  1. Environmental Conditions Favoring Fe²⁺
                    1. Specific Fe²⁺ Transporters
                      1. Anaerobic and Microaerobic Niches
                      2. Direct Host Protein Binding
                        1. Surface Receptors for Transferrin
                          1. Lactoferrin-binding Proteins
                            1. Iron Extraction Mechanisms

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                          2. Iron Bioavailability Challenges

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                          4. Siderophore Structure and Function