Iron Transport and Receptors in Bacteria

  1. Intracellular Iron Processing
    1. Iron Release from Siderophores
      1. Reductive Release
        1. Ferric Reductases
          1. Electron Donors
            1. NADH and NADPH Systems
            2. Hydrolytic Release
              1. Esterases
                1. Peptidases
                  1. Siderophore Degradation
                  2. Modification-mediated Release
                    1. Chemical Modifications
                      1. Enzymatic Alterations
                        1. pH-dependent Mechanisms
                      2. Cytoplasmic Iron Trafficking
                        1. Iron-Sulfur Cluster Assembly
                          1. ISC System
                            1. SUF System
                              1. Scaffold Proteins
                                1. Cluster Transfer Mechanisms
                                2. Heme Biosynthesis
                                  1. Protoporphyrin IX Formation
                                    1. Iron Insertion Mechanisms
                                      1. Regulatory Controls
                                    2. Iron Storage Systems
                                      1. Bacterioferritin
                                        1. 24-subunit Structure
                                          1. Iron Mineralization
                                            1. Heme Cofactors
                                            2. Ferritin-like Proteins
                                              1. Dps Proteins
                                                1. DNA Protection Function
                                                  1. Oxidative Stress Response

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                                              6. Periplasmic and Inner Membrane Transport

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                                              8. Iron Homeostasis Regulation