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Biology
Cell Biology
Cell Signaling and Signal Transduction
1. Fundamentals of Cell Communication
2. Signaling Molecules
3. Cellular Receptors
4. G-Protein Coupled Receptor Pathways
5. Enzyme-Linked Receptor Pathways
6. Other Major Signaling Pathways
7. Intracellular Signaling Components and Mechanisms
8. Regulation and Integration of Cellular Signals
9. Cellular Responses to Signaling
10. Signaling in Health and Disease
3.
Cellular Receptors
3.1.
Intracellular Receptors
3.1.1.
Location
3.1.1.1.
Cytoplasmic Receptors
3.1.1.2.
Nuclear Receptors
3.1.2.
Mechanism of Action
3.1.2.1.
Ligand-Activated Transcription Factors
3.1.2.2.
DNA Binding Domains
3.1.2.3.
Hormone Response Elements
3.1.3.
Steroid Hormone Receptor Superfamily
3.1.3.1.
Glucocorticoid Receptors
3.1.3.2.
Estrogen Receptors
3.1.3.3.
Androgen Receptors
3.2.
Cell-Surface Receptors
3.2.1.
General Structure and Function
3.2.1.1.
Extracellular Ligand-Binding Domain
3.2.1.2.
Transmembrane Domain
3.2.1.3.
Intracellular Signaling Domain
3.2.2.
Ion Channel-Linked Receptors
3.2.2.1.
Structure of Ligand-Gated Ion Channels
3.2.2.2.
Mechanism of Channel Opening
3.2.2.3.
Nicotinic Acetylcholine Receptor
3.2.3.
G-Protein Coupled Receptors
3.2.3.1.
Seven-Transmembrane Domain Structure
3.2.3.2.
Ligand Binding Sites
3.2.3.3.
Coupling to G-Proteins
3.2.4.
Enzyme-Linked Receptors
3.2.4.1.
Receptor Tyrosine Kinases
3.2.4.2.
Receptor Serine/Threonine Kinases
3.2.4.3.
Receptor Guanylyl Cyclases
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2. Signaling Molecules
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4. G-Protein Coupled Receptor Pathways