Bacterial Pathogenesis

  1. Bacterial Transmission and Host Entry
    1. Modes of Transmission
      1. Direct Contact Transmission
        1. Person-to-Person Contact
          1. Animal-to-Person Transmission
            1. Zoonotic Diseases
            2. Indirect Contact Transmission
              1. Fomite-Mediated Transmission
                1. Environmental Reservoirs
                  1. Contaminated Surfaces
                  2. Respiratory Transmission
                    1. Droplet Transmission
                      1. Airborne Transmission
                        1. Aerosol Generation and Spread
                        2. Fecal-Oral Transmission
                          1. Waterborne Transmission
                            1. Foodborne Transmission
                              1. Poor Sanitation Conditions
                              2. Vector-Borne Transmission
                                1. Biological Vectors
                                  1. Mechanical Vectors
                                    1. Vector Control Implications
                                    2. Vertical Transmission
                                      1. Maternal-Fetal Transmission
                                        1. Birth Canal Transmission
                                      2. Portals of Entry
                                        1. Respiratory Tract
                                          1. Nasal Cavity Entry
                                            1. Upper Respiratory Tract
                                              1. Lower Respiratory Tract
                                                1. Alveolar Entry
                                                2. Gastrointestinal Tract
                                                  1. Oral Cavity
                                                    1. Gastric Environment
                                                      1. Small Intestine
                                                        1. Large Intestine
                                                        2. Genitourinary Tract
                                                          1. Urethral Entry
                                                            1. Vaginal Entry
                                                              1. Bladder Colonization
                                                              2. Skin and Mucous Membranes
                                                                1. Intact Skin Barriers
                                                                  1. Compromised Skin Entry
                                                                    1. Mucous Membrane Penetration
                                                                      1. Conjunctival Entry
                                                                      2. Parenteral Routes
                                                                        1. Insect Bite Transmission
                                                                          1. Needle-Stick Injuries
                                                                            1. Surgical Site Entry
                                                                              1. Wound Contamination
                                                                            2. Host Barriers to Entry
                                                                              1. Physical Barriers
                                                                                1. Skin Structure and Function
                                                                                  1. Mucous Membrane Properties
                                                                                    1. Ciliary Clearance Mechanisms
                                                                                    2. Chemical Barriers
                                                                                      1. Gastric Acid
                                                                                        1. Antimicrobial Peptides
                                                                                          1. Secretory Antibodies
                                                                                          2. Biological Barriers
                                                                                            1. Normal Microbiota Competition
                                                                                              1. Immune Surveillance

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                                                                                          1. Introduction to Bacterial Pathogenesis

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                                                                                          3. Bacterial Adhesion and Colonization