Immunology

  1. Immunopathology
    1. Hypersensitivity Reactions
      1. Type I Hypersensitivity
        1. IgE-Mediated Mechanisms
          1. Mast Cell Degranulation
            1. Allergic Reactions
              1. Anaphylaxis
              2. Type II Hypersensitivity
                1. Antibody-Mediated Cytotoxicity
                  1. Complement-Mediated Lysis
                    1. Clinical Examples
                    2. Type III Hypersensitivity
                      1. Immune Complex Formation
                        1. Tissue Deposition
                          1. Inflammatory Responses
                            1. Clinical Manifestations
                            2. Type IV Hypersensitivity
                              1. T Cell-Mediated Responses
                                1. Delayed-Type Hypersensitivity
                                  1. Contact Sensitivity
                                    1. Granulomatous Reactions
                                  2. Autoimmune Diseases
                                    1. Mechanisms of Autoimmunity
                                      1. Tolerance Breakdown
                                        1. Molecular Mimicry
                                          1. Epitope Spreading
                                            1. Bystander Activation
                                            2. Genetic Factors
                                              1. HLA Associations
                                                1. Non-HLA Genes
                                                  1. Polygenic Inheritance
                                                  2. Environmental Triggers
                                                    1. Infectious Agents
                                                      1. Chemical Exposures
                                                        1. Stress Factors
                                                        2. Systemic Autoimmune Diseases
                                                          1. Systemic Lupus Erythematosus
                                                            1. Rheumatoid Arthritis
                                                              1. Systemic Sclerosis
                                                              2. Organ-Specific Autoimmune Diseases
                                                                1. Type 1 Diabetes
                                                                  1. Multiple Sclerosis
                                                                    1. Autoimmune Thyroid Disease
                                                                  2. Immunodeficiency Disorders
                                                                    1. Primary Immunodeficiencies
                                                                      1. B Cell Deficiencies
                                                                        1. Agammaglobulinemia
                                                                          1. Common Variable Immunodeficiency
                                                                            1. Selective Antibody Deficiencies
                                                                            2. T Cell Deficiencies
                                                                              1. DiGeorge Syndrome
                                                                                1. Chronic Mucocutaneous Candidiasis
                                                                                2. Combined Immunodeficiencies
                                                                                  1. Severe Combined Immunodeficiency
                                                                                    1. Wiskott-Aldrich Syndrome
                                                                                    2. Phagocyte Defects
                                                                                      1. Chronic Granulomatous Disease
                                                                                        1. Leukocyte Adhesion Deficiency
                                                                                        2. Complement Deficiencies
                                                                                          1. Classical Pathway Defects
                                                                                            1. Alternative Pathway Defects
                                                                                          2. Secondary Immunodeficiencies
                                                                                            1. HIV/AIDS
                                                                                              1. Viral Pathogenesis
                                                                                                1. CD4 T Cell Depletion
                                                                                                  1. Opportunistic Infections
                                                                                                  2. Immunosuppressive Therapies
                                                                                                    1. Malnutrition Effects

                                                                                                Previous

                                                                                                8. Host Defense Against Pathogens

                                                                                                Go to top

                                                                                                Next

                                                                                                10. Clinical Immunology Applications