Immunology

  1. Cells and Organs of the Immune System
    1. Hematopoiesis and Immune Cell Development
      1. Hematopoietic Stem Cells
        1. Properties and Characteristics
          1. Self-Renewal and Differentiation
          2. Myeloid Lineage Development
            1. Common Myeloid Progenitor
              1. Granulocyte Development
                1. Monocyte Development
                  1. Dendritic Cell Development
                  2. Lymphoid Lineage Development
                    1. Common Lymphoid Progenitor
                      1. B Cell Development
                        1. T Cell Development
                          1. Natural Killer Cell Development
                        2. Primary Lymphoid Organs
                          1. Bone Marrow
                            1. Structure and Organization
                              1. Site of Hematopoiesis
                                1. B Cell Development and Maturation
                                  1. Microenvironment
                                  2. Thymus
                                    1. Structure and Organization
                                      1. T Cell Maturation
                                        1. Thymic Selection Processes
                                      2. Secondary Lymphoid Organs
                                        1. Spleen
                                          1. Anatomical Structure
                                            1. White Pulp Organization
                                              1. Red Pulp Function
                                                1. Role in Immune Surveillance
                                                2. Lymph Nodes
                                                  1. Anatomical Structure
                                                    1. Lymphocyte Trafficking
                                                      1. Antigen Presentation
                                                        1. Germinal Center Formation
                                                        2. Mucosa-Associated Lymphoid Tissue
                                                          1. Organization and Function
                                                            1. Gut-Associated Lymphoid Tissue
                                                              1. Peyer's Patches
                                                                1. Isolated Lymphoid Follicles
                                                                  1. Mesenteric Lymph Nodes
                                                                  2. Bronchus-Associated Lymphoid Tissue
                                                                    1. Structure and Function
                                                                      1. Respiratory Immune Defense
                                                                  3. Innate Immune Cells
                                                                    1. Phagocytic Cells
                                                                      1. Macrophages
                                                                        1. Tissue Distribution
                                                                          1. Activation States
                                                                            1. Phagocytic Function
                                                                              1. Antigen Presentation
                                                                              2. Neutrophils
                                                                                1. Morphology and Characteristics
                                                                                  1. Recruitment Mechanisms
                                                                                    1. Antimicrobial Functions
                                                                                      1. Neutrophil Extracellular Traps
                                                                                      2. Dendritic Cells
                                                                                        1. Subtypes and Distribution
                                                                                          1. Antigen Uptake Mechanisms
                                                                                            1. Migration to Lymphoid Organs
                                                                                              1. Antigen Presentation Function
                                                                                            2. Granulocytes
                                                                                              1. Eosinophils
                                                                                                1. Morphology and Characteristics
                                                                                                  1. Role in Parasitic Infections
                                                                                                    1. Involvement in Allergic Responses
                                                                                                    2. Basophils
                                                                                                      1. Morphology and Characteristics
                                                                                                        1. Mediator Release
                                                                                                          1. Role in Inflammation
                                                                                                          2. Mast Cells
                                                                                                            1. Distribution and Characteristics
                                                                                                              1. Degranulation Mechanisms
                                                                                                                1. Role in Allergy and Anaphylaxis
                                                                                                              2. Natural Killer Cells
                                                                                                                1. Phenotype and Characteristics
                                                                                                                  1. Recognition Mechanisms
                                                                                                                    1. Cytotoxic Functions
                                                                                                                      1. Role in Tumor Surveillance
                                                                                                                    2. Adaptive Immune Cells
                                                                                                                      1. B Lymphocytes
                                                                                                                        1. Development Stages
                                                                                                                          1. Surface Markers
                                                                                                                            1. Antibody Production
                                                                                                                              1. Antigen Presentation Function
                                                                                                                              2. T Lymphocytes
                                                                                                                                1. Helper T Cells
                                                                                                                                  1. CD4 Expression
                                                                                                                                    1. Subset Differentiation
                                                                                                                                      1. Cytokine Production
                                                                                                                                      2. Cytotoxic T Cells
                                                                                                                                        1. CD8 Expression
                                                                                                                                          1. Target Recognition
                                                                                                                                            1. Killing Mechanisms
                                                                                                                                            2. Regulatory T Cells
                                                                                                                                              1. Phenotypic Markers
                                                                                                                                                1. Suppressive Functions
                                                                                                                                                  1. Development and Maintenance