Immunology

  1. B Cell Biology and Antibody Responses
    1. B Cell Receptor and Antibody Structure
      1. Immunoglobulin Structure
        1. Heavy Chains
          1. Light Chains
            1. Variable Regions
              1. Constant Regions
              2. Antibody Classes
                1. IgM
                  1. Structure
                    1. Distribution
                      1. Functions
                      2. IgG
                        1. Subclasses
                          1. Distribution
                            1. Functions
                            2. IgA
                              1. Secretory Form
                                1. Mucosal Immunity
                                2. IgE
                                  1. Allergic Responses
                                    1. Parasite Defense
                                    2. IgD
                                      1. B Cell Receptor
                                        1. Function
                                      2. Antibody Functions
                                        1. Neutralization
                                          1. Opsonization
                                            1. Complement Activation
                                              1. Antibody-Dependent Cellular Cytotoxicity
                                            2. B Cell Development
                                              1. Bone Marrow Development
                                                1. Pro-B Cell Stage
                                                  1. Pre-B Cell Stage
                                                    1. Immature B Cell Stage
                                                    2. Immunoglobulin Gene Rearrangement
                                                      1. Heavy Chain Rearrangement
                                                        1. Light Chain Rearrangement
                                                          1. Allelic Exclusion
                                                          2. B Cell Tolerance
                                                            1. Central Tolerance Mechanisms
                                                              1. Receptor Editing
                                                                1. Clonal Deletion
                                                                  1. Anergy Induction
                                                                2. B Cell Activation and Responses
                                                                  1. T-Independent Responses
                                                                    1. Type 1 T-Independent Antigens
                                                                      1. Type 2 T-Independent Antigens
                                                                        1. Response Characteristics
                                                                        2. T-Dependent Responses
                                                                          1. Helper T Cell Interaction
                                                                            1. Germinal Center Formation
                                                                              1. Somatic Hypermutation
                                                                                1. Affinity Maturation
                                                                                  1. Class Switch Recombination
                                                                                  2. Plasma Cell Differentiation
                                                                                    1. Transcriptional Control
                                                                                      1. Antibody Secretion
                                                                                        1. Lifespan and Maintenance
                                                                                        2. Memory B Cell Formation
                                                                                          1. Differentiation Pathways
                                                                                            1. Phenotypic Characteristics
                                                                                              1. Recall Responses

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                                                                                          5. T Cell Biology

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                                                                                          7. Immune System Regulation