Endocrinology

  1. The Hypothalamic-Pituitary Axis
    1. Anatomy and Development
      1. Hypothalamic Structure
        1. Nuclei and Regions
          1. Neuronal Populations
          2. Pituitary Gland Structure
            1. Anterior Pituitary
              1. Posterior Pituitary
                1. Intermediate Lobe
                2. Vascular Connections
                  1. Hypophyseal Portal System
                    1. Blood Supply
                    2. Embryological Development
                      1. Rathke's Pouch
                        1. Neural Crest Origins
                      2. Hypothalamic Hormones
                        1. Releasing Hormones
                          1. Gonadotropin-Releasing Hormone
                            1. Structure and Synthesis
                              1. Pulsatile Secretion
                                1. Regulation
                                2. Thyrotropin-Releasing Hormone
                                  1. Structure and Function
                                    1. Regulation
                                    2. Corticotropin-Releasing Hormone
                                      1. Structure and Function
                                        1. Stress Response
                                        2. Growth Hormone-Releasing Hormone
                                          1. Structure and Function
                                            1. Regulation
                                          2. Inhibiting Hormones
                                            1. Somatostatin
                                              1. Structure and Function
                                                1. Multiple Target Tissues
                                                2. Dopamine
                                                  1. Prolactin Inhibition
                                                    1. Tuberoinfundibular Pathway
                                                3. Anterior Pituitary Hormones
                                                  1. Cell Types and Hormone Production
                                                    1. Somatotrophs
                                                      1. Lactotrophs
                                                        1. Corticotrophs
                                                          1. Thyrotrophs
                                                            1. Gonadotrophs
                                                            2. Growth Hormone
                                                              1. Structure and Synthesis
                                                                1. Regulation of Secretion
                                                                  1. GHRH Stimulation
                                                                    1. Somatostatin Inhibition
                                                                      1. Metabolic Influences
                                                                      2. Physiological Actions
                                                                        1. Growth Effects
                                                                          1. Metabolic Effects
                                                                            1. IGF-1 Mediation
                                                                          2. Prolactin
                                                                            1. Structure and Synthesis
                                                                              1. Regulation of Secretion
                                                                                1. Dopamine Inhibition
                                                                                  1. TRH Stimulation
                                                                                  2. Physiological Functions
                                                                                    1. Lactation
                                                                                      1. Reproductive Effects
                                                                                    2. ACTH
                                                                                      1. Structure and Synthesis
                                                                                        1. Regulation of Secretion
                                                                                          1. CRH Stimulation
                                                                                            1. Cortisol Feedback
                                                                                            2. Effects on Adrenal Cortex
                                                                                            3. TSH
                                                                                              1. Structure and Synthesis
                                                                                                1. Regulation of Secretion
                                                                                                  1. TRH Stimulation
                                                                                                    1. Thyroid Hormone Feedback
                                                                                                    2. Effects on Thyroid Gland
                                                                                                    3. Gonadotropins
                                                                                                      1. FSH
                                                                                                        1. Structure and Function
                                                                                                          1. Regulation
                                                                                                            1. Role in Gametogenesis
                                                                                                            2. LH
                                                                                                              1. Structure and Function
                                                                                                                1. Regulation
                                                                                                                  1. Role in Steroidogenesis
                                                                                                              2. Posterior Pituitary Hormones
                                                                                                                1. Hormone Synthesis and Transport
                                                                                                                  1. Magnocellular Neurons
                                                                                                                    1. Axonal Transport
                                                                                                                      1. Storage in Nerve Terminals
                                                                                                                      2. Antidiuretic Hormone
                                                                                                                        1. Structure and Synthesis
                                                                                                                          1. Regulation of Secretion
                                                                                                                            1. Osmotic Stimuli
                                                                                                                              1. Volume Stimuli
                                                                                                                                1. Non-Osmotic Stimuli
                                                                                                                                2. Physiological Actions
                                                                                                                                  1. Water Reabsorption
                                                                                                                                    1. Vascular Effects
                                                                                                                                  2. Oxytocin
                                                                                                                                    1. Structure and Synthesis
                                                                                                                                      1. Regulation of Secretion
                                                                                                                                        1. Mechanical Stimuli
                                                                                                                                          1. Neural Reflexes
                                                                                                                                          2. Physiological Actions
                                                                                                                                            1. Uterine Contractions
                                                                                                                                              1. Milk Ejection
                                                                                                                                                1. Social Bonding

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                                                                                                                                          3. Mechanisms of Hormone Action

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                                                                                                                                          5. The Thyroid Gland