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Chemistry
Applied and Interdisciplinary Chemistry
Biophysical Chemistry
1. Introduction to Biophysical Chemistry
2. Biological Molecules as Physical Systems
3. Water and the Biological Environment
4. Fundamental Physical Forces
5. Thermodynamics of Biological Systems
6. Chemical Kinetics and Dynamics
7. Macromolecular Structure
8. Spectroscopic Methods
9. Structural Determination Methods
10. Hydrodynamics and Transport
11. Molecular Interactions and Binding
12. Statistical Mechanics Applications
3.
Water and the Biological Environment
3.1.
Structure and Properties of Water
3.1.1.
Molecular Geometry
3.1.2.
Electronic Structure
3.1.3.
Polarity and Dipole Moment
3.1.4.
Physical Properties
3.2.
Hydrogen Bonding
3.2.1.
Geometric Requirements
3.2.2.
Energetics
3.2.3.
Network Formation
3.2.4.
Temperature Dependence
3.3.
The Hydrophobic Effect
3.3.1.
Thermodynamic Origin
3.3.2.
Entropy Contributions
3.3.3.
Temperature Dependence
3.3.4.
Biological Significance
3.4.
Aqueous Solutions
3.4.1.
Ion Hydration
3.4.2.
Activity Coefficients
3.4.3.
Debye-Hückel Theory
3.4.4.
Buffer Systems
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2. Biological Molecules as Physical Systems
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4. Fundamental Physical Forces