Biophysical Chemistry

  1. Biological Molecules as Physical Systems
    1. Proteins
      1. Amino Acid Properties
        1. Chemical Structure
          1. Side Chain Classifications
            1. Ionization States
              1. Hydrophobicity Scales
              2. Peptide Bond Formation
                1. Covalent Bond Characteristics
                  1. Geometric Constraints
                    1. Resonance Stabilization
                    2. Structural Hierarchy
                      1. Primary Structure
                        1. Secondary Structure
                          1. Tertiary Structure
                            1. Quaternary Structure
                            2. Physical Properties
                              1. Size and Shape
                                1. Charge Distribution
                                  1. Hydrophobic Surface Area
                                2. Nucleic Acids
                                  1. Nucleotide Components
                                    1. Purine Bases
                                      1. Pyrimidine Bases
                                        1. Sugar Moieties
                                          1. Phosphate Groups
                                          2. DNA Structure
                                            1. Double Helix Geometry
                                              1. Base Pairing Rules
                                                1. Groove Structure
                                                  1. Structural Polymorphism
                                                  2. RNA Structure
                                                    1. Single-Strand Folding
                                                      1. Secondary Structure Elements
                                                        1. Tertiary Structure Formation
                                                          1. Catalytic RNA
                                                          2. Physical Properties
                                                            1. Persistence Length
                                                              1. Flexibility
                                                                1. Charge Density
                                                              2. Lipids and Membranes
                                                                1. Lipid Classifications
                                                                  1. Phospholipids
                                                                    1. Sterols
                                                                      1. Glycolipids
                                                                      2. Membrane Structure
                                                                        1. Bilayer Organization
                                                                          1. Asymmetry
                                                                            1. Lipid Rafts
                                                                            2. Membrane Dynamics
                                                                              1. Lateral Diffusion
                                                                                1. Flip-Flop Motion
                                                                                  1. Phase Transitions
                                                                                2. Carbohydrates
                                                                                  1. Monosaccharide Structure
                                                                                    1. Stereochemistry
                                                                                      1. Ring Formation
                                                                                        1. Anomeric Forms
                                                                                        2. Polysaccharide Structure
                                                                                          1. Glycosidic Linkages
                                                                                            1. Branching Patterns
                                                                                              1. Conformational Flexibility
                                                                                              2. Biological Functions
                                                                                                1. Energy Storage
                                                                                                  1. Structural Support
                                                                                                    1. Cell Recognition

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                                                                                                1. Introduction to Biophysical Chemistry

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                                                                                                3. Water and the Biological Environment