Cell Biology

  1. Cell Death and Disease
    1. Programmed Cell Death
      1. Apoptosis
        1. Apoptotic Pathways
          1. Intrinsic Pathway
            1. Extrinsic Pathway
            2. Caspase Activation
              1. Initiator Caspases
                1. Effector Caspases
                2. Apoptotic Signals
                  1. DNA Damage
                    1. Growth Factor Withdrawal
                    2. Apoptosis in Development
                      1. Tissue Sculpting
                        1. Cell Number Regulation
                      2. Autophagy
                        1. Macroautophagy
                          1. Microautophagy
                            1. Chaperone-Mediated Autophagy
                            2. Necrosis
                              1. Accidental Cell Death
                                1. Inflammatory Response
                              2. Cancer Biology
                                1. Cancer Cell Characteristics
                                  1. Uncontrolled Proliferation
                                    1. Loss of Growth Control
                                      1. Invasion and Metastasis
                                      2. Oncogenes
                                        1. Growth Factor Receptors
                                          1. Signal Transduction Proteins
                                            1. Transcription Factors
                                            2. Tumor Suppressor Genes
                                              1. p53 Function
                                                1. Rb Function
                                                  1. DNA Repair Genes
                                                  2. Hallmarks of Cancer
                                                    1. Self-Sufficiency in Growth Signals
                                                      1. Insensitivity to Growth Inhibition
                                                        1. Evasion of Apoptosis
                                                          1. Unlimited Replicative Potential
                                                            1. Sustained Angiogenesis
                                                              1. Tissue Invasion and Metastasis
                                                              2. Cancer Development
                                                                1. Multistep Carcinogenesis
                                                                  1. Genetic Instability
                                                                    1. Clonal Evolution
                                                                  2. Cellular Aging
                                                                    1. Senescence
                                                                      1. Replicative Senescence
                                                                        1. Stress-Induced Senescence
                                                                          1. Senescence-Associated Phenotypes
                                                                          2. Telomeres and Aging
                                                                            1. Telomere Shortening
                                                                              1. Telomerase Activity
                                                                                1. Cellular Lifespan
                                                                                2. Molecular Mechanisms of Aging
                                                                                  1. DNA Damage Accumulation
                                                                                    1. Protein Aggregation
                                                                                      1. Mitochondrial Dysfunction

                                                                                  Previous

                                                                                  8. Gene Expression and Regulation

                                                                                  Go to top

                                                                                  Next

                                                                                  10. Experimental Methods in Cell Biology