Virology

  1. Viral Structure and Morphology
    1. The Virion
      1. Definition and Function
        1. Virion Size Range
          1. Virion Shape Diversity
          2. Viral Genome
            1. Nucleic Acid Types
              1. DNA Viruses
                1. Single-Stranded DNA
                  1. Double-Stranded DNA
                  2. RNA Viruses
                    1. Single-Stranded RNA
                      1. Positive-Sense RNA
                        1. Negative-Sense RNA
                        2. Double-Stranded RNA
                      2. Genome Structure
                        1. Linear Genomes
                          1. Circular Genomes
                            1. Segmented Genomes
                              1. Monopartite vs. Multipartite Genomes
                              2. Genome Size and Coding Capacity
                                1. Terminal Structures
                                  1. 5' Cap
                                    1. Poly(A) Tail
                                      1. Terminal Repeats
                                    2. The Capsid
                                      1. Protein Subunits
                                        1. Capsomeres
                                          1. Functions of the Capsid
                                            1. Protection of the Genome
                                              1. Host Cell Attachment
                                                1. Immune Evasion
                                                2. Capsid Symmetry
                                                  1. Helical Symmetry
                                                    1. Icosahedral Symmetry
                                                      1. Complex Symmetry
                                                      2. Capsid Assembly Mechanisms
                                                      3. The Viral Envelope
                                                        1. Origin of the Envelope
                                                          1. Host Cell Plasma Membrane
                                                            1. Host Cell Nuclear Membrane
                                                              1. Host Cell Endoplasmic Reticulum
                                                              2. Composition of the Envelope
                                                                1. Lipids
                                                                  1. Envelope Proteins
                                                                    1. Glycoproteins
                                                                    2. Functions of the Envelope
                                                                      1. Host Cell Recognition
                                                                        1. Membrane Fusion
                                                                        2. Enveloped vs. Non-enveloped Viruses
                                                                          1. Stability in the Environment
                                                                            1. Modes of Transmission
                                                                          2. Other Viral Proteins
                                                                            1. Enzymes
                                                                              1. Polymerases
                                                                                1. Proteases
                                                                                  1. Integrase
                                                                                    1. Reverse Transcriptase
                                                                                      1. Neuraminidase
                                                                                      2. Structural Proteins
                                                                                        1. Non-structural Proteins
                                                                                          1. Accessory Proteins

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                                                                                        1. Introduction to Virology

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                                                                                        3. Viral Classification and Taxonomy