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Biology
Genetics and Genomics
Population Genetics
1. Introduction to Population Genetics
2. Genetic Variation in Populations
3. The Hardy-Weinberg Principle
4. Mutation as an Evolutionary Force
5. Genetic Drift
6. Natural Selection
7. Gene Flow and Migration
8. Mating Systems and Population Structure
9. Molecular Population Genetics
10. Quantitative Genetics
11. Population Genetics Applications
12. Advanced Topics
9.
Molecular Population Genetics
9.1.
Molecular Markers
9.1.1.
Types of Markers
9.1.1.1.
Allozymes
9.1.1.2.
RFLPs
9.1.1.3.
Microsatellites
9.1.1.4.
SNPs
9.1.1.5.
Mitochondrial DNA
9.1.1.6.
Chloroplast DNA
9.1.2.
Marker Properties
9.1.2.1.
Inheritance Patterns
9.1.2.2.
Mutation Rates
9.1.2.3.
Level of Polymorphism
9.2.
DNA Sequence Analysis
9.2.1.
Sequence Alignment
9.2.2.
Polymorphism Detection
9.2.3.
Phylogenetic Relationships
9.3.
Neutral Theory
9.3.1.
Kimura's Neutral Theory
9.3.2.
Nearly Neutral Theory
9.3.3.
Predictions
9.3.3.1.
Molecular Clock
9.3.3.2.
Polymorphism Patterns
9.3.3.3.
Substitution Rates
9.4.
Tests of Neutrality
9.4.1.
Tajima's D
9.4.2.
Fu and Li's Tests
9.4.3.
McDonald-Kreitman Test
9.4.4.
HKA Test
9.5.
Detecting Selection
9.5.1.
Synonymous vs Non-synonymous Sites
9.5.2.
Ka/Ks Ratios
9.5.3.
Codon Usage Bias
9.5.4.
Linkage Disequilibrium Patterns
9.6.
Population History Inference
9.6.1.
Coalescent Theory
9.6.2.
Demographic Inference
9.6.3.
Migration Patterns
9.6.4.
Population Bottlenecks
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8. Mating Systems and Population Structure
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10. Quantitative Genetics