Biomaterials and Tissue Engineering

9.

Scaffold Design and Engineering

9.1.

Design Requirements

9.1.1.

Biocompatibility

9.1.2.

Biodegradability

9.1.3.

Mechanical Properties

9.1.4.

Porosity and Pore Structure

9.1.4.1.

Pore Size Requirements

9.1.4.2.

Pore Interconnectivity

9.1.4.3.

Porosity Percentage

9.1.5.

Surface Properties

9.1.5.1.

Surface Chemistry

9.1.5.2.

Surface Topography

9.1.5.3.

9.1.6.

Sterilizability

9.2.

Scaffold Architecture

9.2.1.

Macro-architecture

9.2.2.

Micro-architecture

9.2.3.

Nano-architecture

9.2.4.

Hierarchical Structures

9.3.

Fabrication Techniques

9.3.1.

Conventional Methods

9.3.1.1.

Solvent Casting

9.3.1.2.

Particulate Leaching

9.3.1.3.

9.3.1.4.

Phase Separation

9.3.1.5.

9.3.1.6.

9.3.2.

Advanced Manufacturing

9.3.2.1.

Electrospinning

9.3.2.1.1.

Process Parameters

9.3.2.1.2.

Fiber Morphology

9.3.2.1.3.

Collector Types

9.3.2.2.

3D Printing Technologies

9.3.2.2.1.

Fused Deposition Modeling

9.3.2.2.2.

Stereolithography

9.3.2.2.3.

Selective Laser Sintering

9.3.2.2.4.

Inkjet Printing

9.3.2.2.5.

Multi-material Printing

9.3.2.3.

9.3.2.3.1.

Bioink Development

9.3.2.3.2.

9.3.2.3.3.

Tissue Printing

9.3.2.3.4.

9.3.3.

Textile Technologies

9.3.3.1.

9.3.3.2.

9.3.3.3.

9.3.3.4.

Non-woven Techniques

9.4.

Decellularized Matrices

9.4.1.

Decellularization Methods

9.4.1.1.

Physical Methods

9.4.1.2.

Chemical Methods

9.4.1.3.

Enzymatic Methods

9.4.2.

ECM Preservation

9.4.3.

Recellularization

9.5.

Surface Modification

9.5.1.

Chemical Modification

9.5.2.

Physical Modification

9.5.3.

Biological Modification

9.5.4.

Coating Techniques

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10. Bioreactor Systems