Biomaterials and Tissue Engineering

  1. Extracellular Matrix
    1. ECM Composition
      1. Fibrous Proteins
        1. Collagen Types
          1. Type I Collagen
            1. Type II Collagen
              1. Type III Collagen
                1. Other Collagen Types
                2. Elastin
                  1. Structure
                    1. Assembly
                    2. Fibronectin
                      1. Domains
                        1. Cell Binding
                        2. Laminin
                          1. Structure
                            1. Basement Membrane
                          2. Proteoglycans
                            1. Structure
                              1. Types
                                1. Functions
                                2. Glycosaminoglycans
                                  1. Hyaluronic Acid
                                    1. Chondroitin Sulfate
                                      1. Heparan Sulfate
                                        1. Dermatan Sulfate
                                      2. ECM Organization
                                        1. Tissue-Specific ECM
                                          1. Hierarchical Structure
                                            1. Cross-linking
                                              1. Remodeling
                                              2. ECM Functions
                                                1. Structural Support
                                                  1. Cell Adhesion
                                                    1. Signal Transduction
                                                      1. Growth Factor Sequestration
                                                        1. Cell Migration
                                                        2. Cell-ECM Interactions
                                                          1. Integrins
                                                            1. Structure
                                                              1. Signaling
                                                                1. Types
                                                                2. Focal Adhesions
                                                                  1. Mechanotransduction
                                                                    1. ECM Degradation
                                                                      1. Matrix Metalloproteinases
                                                                        1. Regulation

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                                                                    5. Cell Sources for Tissue Engineering

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                                                                    7. Growth Factors and Signaling