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Engineering
Biomedical Engineering
Biomaterials and Tissue Engineering
1. Introduction to Biomaterials and Tissue Engineering
2. Materials Science Fundamentals
3. Classes of Biomaterials
4. Cell Biology for Tissue Engineering
5. Cell Sources for Tissue Engineering
6. Extracellular Matrix
7. Growth Factors and Signaling
8. Biocompatibility and Host Response
9. Scaffold Design and Engineering
10. Bioreactor Systems
11. Characterization Methods
12. Tissue Engineering Applications
13. Drug Delivery Systems
14. Medical Device Applications
15. Regulatory and Clinical Translation
16. Emerging Technologies and Future Directions
Cell Sources for Tissue Engineering
Classification of Cell Sources
Autologous Cells
Advantages
Limitations
Harvesting Methods
Allogeneic Cells
Immunological Considerations
HLA Matching
Immunosuppression
Xenogeneic Cells
Species Barriers
Zoonotic Risks
Genetic Modifications
Stem Cells
Stem Cell Properties
Self-Renewal
Potency
Differentiation
Embryonic Stem Cells
Derivation
Pluripotency
Differentiation Protocols
Ethical Issues
Adult Stem Cells
Mesenchymal Stem Cells
Sources
Characterization
Differentiation Potential
Immunomodulatory Properties
Hematopoietic Stem Cells
Bone Marrow Niche
Mobilization
Neural Stem Cells
Adipose-Derived Stem Cells
Other Adult Stem Cell Types
Induced Pluripotent Stem Cells
Reprogramming Factors
Methods of Induction
Characterization
Safety Concerns
Primary Cells
Isolation Methods
Culture Conditions
Phenotype Maintenance
Passage Effects
Cell Lines
Immortalized Cell Lines
Advantages and Limitations
Commonly Used Cell Lines
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4. Cell Biology for Tissue Engineering
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6. Extracellular Matrix