UsefulLinks
Biology
Other Biological Fields
Systems Biology
1. Introduction to Systems Biology
2. Mathematical Foundations
3. High-Throughput Experimental Technologies
4. Bioinformatics and Data Analysis
5. Network Biology
6. Mathematical Modeling
7. Dynamic Systems Analysis
8. Multiscale and Spatial Modeling
9. Single-Cell Systems Biology
10. Applications in Systems Medicine
11. Drug Discovery and Development
12. Synthetic Biology
13. Emerging Technologies and Future Directions
14. Ethical and Societal Considerations
11.
Drug Discovery and Development
11.1.
Systems Pharmacology
11.1.1.
Drug-Target Networks
11.1.1.1.
Polypharmacology
11.1.1.2.
Off-Target Effects
11.1.1.3.
Drug Repurposing
11.1.2.
Pharmacokinetic Modeling
11.1.2.1.
ADMET Properties
11.1.2.2.
Physiologically-Based Models
11.1.2.3.
Population Pharmacokinetics
11.1.3.
Pharmacodynamic Modeling
11.1.3.1.
Dose-Response Relationships
11.1.3.2.
Mechanism-Based Models
11.1.3.3.
Biomarker-Response Models
11.2.
Target Identification and Validation
11.2.1.
Network-Based Target Discovery
11.2.1.1.
Essential Gene Analysis
11.2.1.2.
Druggability Assessment
11.2.1.3.
Target Prioritization
11.2.2.
Experimental Validation
11.2.2.1.
Functional Assays
11.2.2.2.
Animal Models
11.2.2.3.
Clinical Validation
11.3.
Drug Design and Optimization
11.3.1.
Structure-Based Drug Design
11.3.1.1.
Molecular Docking
11.3.1.2.
Virtual Screening
11.3.1.3.
Lead Optimization
11.3.2.
Systems-Based Design
11.3.2.1.
Network Pharmacology
11.3.2.2.
Multi-Target Drugs
11.3.2.3.
Combination Therapy Design
11.4.
Clinical Trial Design
11.4.1.
Biomarker-Driven Trials
11.4.1.1.
Patient Stratification
11.4.1.2.
Companion Diagnostics
11.4.1.3.
Adaptive Designs
11.4.2.
Systems Medicine Approaches
11.4.2.1.
Precision Medicine
11.4.2.2.
Personalized Dosing
11.4.2.3.
Treatment Response Prediction
Previous
10. Applications in Systems Medicine
Go to top
Next
12. Synthetic Biology