Stroke and Neurological Disorders

  1. Cerebrovascular Disease: Stroke
    1. Definition and Epidemiology
      1. Stroke Definition
        1. WHO Definition
          1. Clinical Criteria
            1. Tissue-Based Definition
            2. Epidemiological Measures
              1. Incidence Rates
                1. Prevalence Data
                  1. Age-Adjusted Rates
                  2. Global Burden
                    1. Worldwide Statistics
                      1. Regional Variations
                        1. Developing vs Developed Countries
                        2. Mortality and Morbidity
                          1. Case Fatality Rates
                            1. Disability-Adjusted Life Years
                              1. Economic Burden
                            2. Stroke Classification
                              1. Ischemic Stroke
                                1. Large Artery Atherosclerosis
                                  1. Extracranial Carotid Disease
                                    1. Intracranial Atherosclerosis
                                      1. Vertebrobasilar Disease
                                      2. Cardioembolism
                                        1. Atrial Fibrillation
                                          1. Valvular Heart Disease
                                            1. Cardiomyopathy
                                              1. Paradoxical Embolism
                                              2. Small Vessel Disease
                                                1. Lacunar Infarcts
                                                  1. Microangiopathy
                                                    1. Lipohyalinosis
                                                    2. Other Determined Etiology
                                                      1. Arterial Dissection
                                                        1. Vasculitis
                                                          1. Hypercoagulable States
                                                            1. Sickle Cell Disease
                                                            2. Cryptogenic Stroke
                                                              1. Embolic Stroke of Undetermined Source
                                                                1. Diagnostic Workup
                                                              2. Hemorrhagic Stroke
                                                                1. Intracerebral Hemorrhage
                                                                  1. Primary ICH
                                                                    1. Hypertensive Hemorrhage
                                                                      1. Cerebral Amyloid Angiopathy
                                                                        1. Lobar Hemorrhage
                                                                        2. Secondary ICH
                                                                          1. Arteriovenous Malformations
                                                                            1. Aneurysmal Rupture
                                                                            2. Location-Based Classification
                                                                              1. Deep Hemorrhage
                                                                                1. Lobar Hemorrhage
                                                                                  1. Cerebellar Hemorrhage
                                                                                    1. Brainstem Hemorrhage
                                                                                  2. Subarachnoid Hemorrhage
                                                                                    1. Aneurysmal SAH
                                                                                      1. Saccular Aneurysms
                                                                                        1. Fusiform Aneurysms
                                                                                          1. Mycotic Aneurysms
                                                                                          2. Non-Aneurysmal SAH
                                                                                            1. Perimesencephalic SAH
                                                                                              1. Arteriovenous Malformations
                                                                                                1. Spinal Vascular Malformations
                                                                                            2. Transient Ischemic Attack
                                                                                              1. Definition Evolution
                                                                                                1. Time-Based vs Tissue-Based
                                                                                                  1. Clinical Significance
                                                                                                    1. Risk Stratification
                                                                                                      1. ABCD2 Score
                                                                                                        1. Imaging Findings
                                                                                                    2. Pathophysiology
                                                                                                      1. Ischemic Pathophysiology
                                                                                                        1. Cerebral Blood Flow Thresholds
                                                                                                          1. Normal CBF Values
                                                                                                            1. Ischemic Penumbra
                                                                                                              1. Infarct Core
                                                                                                              2. Ischemic Cascade
                                                                                                                1. Energy Failure
                                                                                                                  1. ATP Depletion
                                                                                                                    1. Ion Pump Failure
                                                                                                                      1. Membrane Depolarization
                                                                                                                      2. Excitotoxicity
                                                                                                                        1. Glutamate Release
                                                                                                                          1. NMDA Receptor Activation
                                                                                                                            1. Calcium Influx
                                                                                                                            2. Oxidative Stress
                                                                                                                              1. Free Radical Formation
                                                                                                                                1. Lipid Peroxidation
                                                                                                                                  1. Antioxidant Depletion
                                                                                                                                  2. Inflammation
                                                                                                                                    1. Microglial Activation
                                                                                                                                      1. Cytokine Release
                                                                                                                                        1. Leukocyte Infiltration
                                                                                                                                        2. Apoptosis
                                                                                                                                          1. Caspase Activation
                                                                                                                                            1. DNA Fragmentation
                                                                                                                                              1. Cell Death Pathways
                                                                                                                                              2. Blood-Brain Barrier Disruption
                                                                                                                                                1. Tight Junction Breakdown
                                                                                                                                                  1. Vasogenic Edema
                                                                                                                                                    1. Hemorrhagic Transformation
                                                                                                                                                  2. Collateral Circulation
                                                                                                                                                    1. Primary Collaterals
                                                                                                                                                      1. Secondary Collaterals
                                                                                                                                                        1. Collateral Assessment
                                                                                                                                                      2. Hemorrhagic Pathophysiology
                                                                                                                                                        1. Vessel Rupture Mechanisms
                                                                                                                                                          1. Hypertensive Changes
                                                                                                                                                            1. Amyloid Deposition
                                                                                                                                                              1. Structural Abnormalities
                                                                                                                                                              2. Hematoma Formation
                                                                                                                                                                1. Initial Bleeding
                                                                                                                                                                  1. Hematoma Expansion
                                                                                                                                                                    1. Mass Effect
                                                                                                                                                                    2. Secondary Injury
                                                                                                                                                                      1. Perihematomal Edema
                                                                                                                                                                        1. Inflammatory Response
                                                                                                                                                                          1. Toxic Effects of Blood
                                                                                                                                                                            1. Hydrocephalus
                                                                                                                                                                            2. Intracranial Pressure
                                                                                                                                                                              1. Monro-Kellie Doctrine
                                                                                                                                                                                1. Herniation Syndromes
                                                                                                                                                                                  1. Cerebral Perfusion Pressure
                                                                                                                                                                              2. Risk Factors and Etiology
                                                                                                                                                                                1. Non-Modifiable Risk Factors
                                                                                                                                                                                  1. Age
                                                                                                                                                                                    1. Stroke Risk by Decade
                                                                                                                                                                                    2. Sex and Gender
                                                                                                                                                                                      1. Sex Differences in Risk
                                                                                                                                                                                        1. Hormonal Influences
                                                                                                                                                                                        2. Race and Ethnicity
                                                                                                                                                                                          1. Population-Specific Risks
                                                                                                                                                                                            1. Genetic Factors
                                                                                                                                                                                              1. Environmental Influences
                                                                                                                                                                                              2. Genetic Factors
                                                                                                                                                                                                1. Single Gene Disorders
                                                                                                                                                                                                  1. Polygenic Risk Scores
                                                                                                                                                                                                    1. Family History Impact
                                                                                                                                                                                                  2. Modifiable Risk Factors
                                                                                                                                                                                                    1. Hypertension
                                                                                                                                                                                                      1. Blood Pressure Targets
                                                                                                                                                                                                        1. Antihypertensive Medications
                                                                                                                                                                                                          1. Resistant Hypertension
                                                                                                                                                                                                          2. Atrial Fibrillation
                                                                                                                                                                                                            1. Stroke Risk Assessment
                                                                                                                                                                                                              1. Anticoagulation Decisions
                                                                                                                                                                                                                1. Rhythm vs Rate Control
                                                                                                                                                                                                                2. Diabetes Mellitus
                                                                                                                                                                                                                  1. Glycemic Control
                                                                                                                                                                                                                    1. Diabetic Complications
                                                                                                                                                                                                                      1. Medication Effects
                                                                                                                                                                                                                      2. Dyslipidemia
                                                                                                                                                                                                                        1. Lipid Targets
                                                                                                                                                                                                                          1. Statin Therapy
                                                                                                                                                                                                                            1. Novel Lipid Therapies
                                                                                                                                                                                                                            2. Smoking
                                                                                                                                                                                                                              1. Dose-Response Relationship
                                                                                                                                                                                                                                1. Cessation Benefits
                                                                                                                                                                                                                                  1. Secondhand Smoke
                                                                                                                                                                                                                                  2. Physical Inactivity
                                                                                                                                                                                                                                    1. Exercise Recommendations
                                                                                                                                                                                                                                      1. Sedentary Behavior
                                                                                                                                                                                                                                      2. Obesity
                                                                                                                                                                                                                                        1. BMI and Stroke Risk
                                                                                                                                                                                                                                          1. Abdominal Obesity
                                                                                                                                                                                                                                            1. Weight Loss Benefits
                                                                                                                                                                                                                                            2. Alcohol Consumption
                                                                                                                                                                                                                                              1. J-Shaped Curve
                                                                                                                                                                                                                                                1. Heavy Drinking Risks
                                                                                                                                                                                                                                                  1. Binge Drinking
                                                                                                                                                                                                                                                  2. Sleep Disorders
                                                                                                                                                                                                                                                    1. Sleep Apnea
                                                                                                                                                                                                                                                      1. Sleep Duration
                                                                                                                                                                                                                                                        1. Sleep Quality
                                                                                                                                                                                                                                                      2. Emerging Risk Factors
                                                                                                                                                                                                                                                        1. Air Pollution
                                                                                                                                                                                                                                                          1. Psychosocial Stress
                                                                                                                                                                                                                                                            1. Inflammatory Markers
                                                                                                                                                                                                                                                              1. Migraine
                                                                                                                                                                                                                                                                1. Periodontal Disease
                                                                                                                                                                                                                                                              2. Clinical Presentation
                                                                                                                                                                                                                                                                1. General Stroke Symptoms
                                                                                                                                                                                                                                                                  1. Sudden Onset
                                                                                                                                                                                                                                                                    1. Focal Neurological Deficits
                                                                                                                                                                                                                                                                      1. Time Course Patterns
                                                                                                                                                                                                                                                                        1. Severity Assessment
                                                                                                                                                                                                                                                                        2. Motor Symptoms
                                                                                                                                                                                                                                                                          1. Hemiparesis
                                                                                                                                                                                                                                                                            1. Upper Motor Neuron Signs
                                                                                                                                                                                                                                                                              1. Distribution Patterns
                                                                                                                                                                                                                                                                                1. Severity Grading
                                                                                                                                                                                                                                                                                2. Dysarthria
                                                                                                                                                                                                                                                                                  1. Speech Articulation
                                                                                                                                                                                                                                                                                    1. Bulbar vs Pseudobulbar
                                                                                                                                                                                                                                                                                    2. Dysphagia
                                                                                                                                                                                                                                                                                      1. Swallowing Phases
                                                                                                                                                                                                                                                                                        1. Aspiration Risk
                                                                                                                                                                                                                                                                                      2. Sensory Symptoms
                                                                                                                                                                                                                                                                                        1. Hemisensory Loss
                                                                                                                                                                                                                                                                                          1. Modality-Specific Deficits
                                                                                                                                                                                                                                                                                            1. Sensory Levels
                                                                                                                                                                                                                                                                                            2. Visual Field Deficits
                                                                                                                                                                                                                                                                                              1. Homonymous Hemianopia
                                                                                                                                                                                                                                                                                                1. Quadrantanopia
                                                                                                                                                                                                                                                                                                  1. Cortical Blindness
                                                                                                                                                                                                                                                                                                  2. Hearing Loss
                                                                                                                                                                                                                                                                                                    1. Central vs Peripheral
                                                                                                                                                                                                                                                                                                  3. Language Disorders
                                                                                                                                                                                                                                                                                                    1. Aphasia Types
                                                                                                                                                                                                                                                                                                      1. Broca's Aphasia
                                                                                                                                                                                                                                                                                                        1. Wernicke's Aphasia
                                                                                                                                                                                                                                                                                                          1. Global Aphasia
                                                                                                                                                                                                                                                                                                            1. Conduction Aphasia
                                                                                                                                                                                                                                                                                                            2. Alexia and Agraphia
                                                                                                                                                                                                                                                                                                              1. Reading Disorders
                                                                                                                                                                                                                                                                                                                1. Writing Disorders
                                                                                                                                                                                                                                                                                                              2. Cognitive Symptoms
                                                                                                                                                                                                                                                                                                                1. Attention Deficits
                                                                                                                                                                                                                                                                                                                  1. Memory Impairment
                                                                                                                                                                                                                                                                                                                    1. Executive Dysfunction
                                                                                                                                                                                                                                                                                                                      1. Neglect Syndromes
                                                                                                                                                                                                                                                                                                                        1. Spatial Neglect
                                                                                                                                                                                                                                                                                                                          1. Personal Neglect
                                                                                                                                                                                                                                                                                                                        2. Behavioral Changes
                                                                                                                                                                                                                                                                                                                          1. Emotional Lability
                                                                                                                                                                                                                                                                                                                            1. Depression
                                                                                                                                                                                                                                                                                                                              1. Anxiety
                                                                                                                                                                                                                                                                                                                                1. Personality Changes
                                                                                                                                                                                                                                                                                                                                2. Vascular Territory Syndromes
                                                                                                                                                                                                                                                                                                                                  1. Anterior Cerebral Artery
                                                                                                                                                                                                                                                                                                                                    1. Leg Weakness
                                                                                                                                                                                                                                                                                                                                      1. Behavioral Changes
                                                                                                                                                                                                                                                                                                                                        1. Urinary Incontinence
                                                                                                                                                                                                                                                                                                                                        2. Middle Cerebral Artery
                                                                                                                                                                                                                                                                                                                                          1. Superior Division
                                                                                                                                                                                                                                                                                                                                            1. Inferior Division
                                                                                                                                                                                                                                                                                                                                              1. Complete MCA Syndrome
                                                                                                                                                                                                                                                                                                                                              2. Posterior Cerebral Artery
                                                                                                                                                                                                                                                                                                                                                1. Visual Field Deficits
                                                                                                                                                                                                                                                                                                                                                  1. Memory Impairment
                                                                                                                                                                                                                                                                                                                                                    1. Alexia without Agraphia
                                                                                                                                                                                                                                                                                                                                                    2. Vertebrobasilar System
                                                                                                                                                                                                                                                                                                                                                      1. Brainstem Syndromes
                                                                                                                                                                                                                                                                                                                                                        1. Cerebellar Syndromes
                                                                                                                                                                                                                                                                                                                                                          1. Cranial Nerve Palsies
                                                                                                                                                                                                                                                                                                                                                          2. Lacunar Syndromes
                                                                                                                                                                                                                                                                                                                                                            1. Pure Motor Stroke
                                                                                                                                                                                                                                                                                                                                                              1. Pure Sensory Stroke
                                                                                                                                                                                                                                                                                                                                                                1. Ataxic Hemiparesis
                                                                                                                                                                                                                                                                                                                                                                  1. Dysarthria-Clumsy Hand
                                                                                                                                                                                                                                                                                                                                                                2. Hemorrhagic Stroke Presentation
                                                                                                                                                                                                                                                                                                                                                                  1. Headache Characteristics
                                                                                                                                                                                                                                                                                                                                                                    1. Nausea and Vomiting
                                                                                                                                                                                                                                                                                                                                                                      1. Altered Consciousness
                                                                                                                                                                                                                                                                                                                                                                        1. Seizures
                                                                                                                                                                                                                                                                                                                                                                          1. Focal Deficits
                                                                                                                                                                                                                                                                                                                                                                        2. Diagnostic Evaluation
                                                                                                                                                                                                                                                                                                                                                                          1. Clinical Assessment
                                                                                                                                                                                                                                                                                                                                                                            1. History Taking
                                                                                                                                                                                                                                                                                                                                                                              1. Symptom Onset
                                                                                                                                                                                                                                                                                                                                                                                1. Risk Factor Assessment
                                                                                                                                                                                                                                                                                                                                                                                  1. Medication History
                                                                                                                                                                                                                                                                                                                                                                                    1. Functional Baseline
                                                                                                                                                                                                                                                                                                                                                                                    2. Physical Examination
                                                                                                                                                                                                                                                                                                                                                                                      1. Vital Signs
                                                                                                                                                                                                                                                                                                                                                                                        1. Cardiovascular Examination
                                                                                                                                                                                                                                                                                                                                                                                          1. Neurological Examination
                                                                                                                                                                                                                                                                                                                                                                                        2. Stroke Scales and Scores
                                                                                                                                                                                                                                                                                                                                                                                          1. NIH Stroke Scale
                                                                                                                                                                                                                                                                                                                                                                                            1. Scale Components
                                                                                                                                                                                                                                                                                                                                                                                              1. Scoring Interpretation
                                                                                                                                                                                                                                                                                                                                                                                                1. Reliability and Validity
                                                                                                                                                                                                                                                                                                                                                                                                2. Modified Rankin Scale
                                                                                                                                                                                                                                                                                                                                                                                                  1. Functional Assessment
                                                                                                                                                                                                                                                                                                                                                                                                    1. Outcome Measurement
                                                                                                                                                                                                                                                                                                                                                                                                    2. Glasgow Coma Scale
                                                                                                                                                                                                                                                                                                                                                                                                      1. Consciousness Assessment
                                                                                                                                                                                                                                                                                                                                                                                                        1. Prognostic Value
                                                                                                                                                                                                                                                                                                                                                                                                        2. ABCD2 Score
                                                                                                                                                                                                                                                                                                                                                                                                          1. TIA Risk Stratification
                                                                                                                                                                                                                                                                                                                                                                                                        3. Neuroimaging
                                                                                                                                                                                                                                                                                                                                                                                                          1. Computed Tomography
                                                                                                                                                                                                                                                                                                                                                                                                            1. Non-Contrast CT
                                                                                                                                                                                                                                                                                                                                                                                                              1. Hemorrhage Detection
                                                                                                                                                                                                                                                                                                                                                                                                                1. Early Ischemic Changes
                                                                                                                                                                                                                                                                                                                                                                                                                  1. Contraindications to Thrombolysis
                                                                                                                                                                                                                                                                                                                                                                                                                  2. CT Angiography
                                                                                                                                                                                                                                                                                                                                                                                                                    1. Vessel Occlusion
                                                                                                                                                                                                                                                                                                                                                                                                                      1. Collateral Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                        1. Aneurysm Detection
                                                                                                                                                                                                                                                                                                                                                                                                                        2. CT Perfusion
                                                                                                                                                                                                                                                                                                                                                                                                                          1. Penumbra Imaging
                                                                                                                                                                                                                                                                                                                                                                                                                            1. Core Infarct
                                                                                                                                                                                                                                                                                                                                                                                                                              1. Mismatch Concepts
                                                                                                                                                                                                                                                                                                                                                                                                                            2. Magnetic Resonance Imaging
                                                                                                                                                                                                                                                                                                                                                                                                                              1. Diffusion-Weighted Imaging
                                                                                                                                                                                                                                                                                                                                                                                                                                1. Acute Infarct Detection
                                                                                                                                                                                                                                                                                                                                                                                                                                  1. ADC Maps
                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Reversible Changes
                                                                                                                                                                                                                                                                                                                                                                                                                                    2. FLAIR Imaging
                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Chronic Changes
                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Leukoaraiosis
                                                                                                                                                                                                                                                                                                                                                                                                                                        2. T2-Weighted Imaging
                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Edema Detection
                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Chronic Infarcts
                                                                                                                                                                                                                                                                                                                                                                                                                                            2. Gradient Echo Imaging
                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Microbleeds
                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Hemorrhage Detection
                                                                                                                                                                                                                                                                                                                                                                                                                                                2. MR Angiography
                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Time-of-Flight
                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Contrast-Enhanced
                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. MR Perfusion
                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Perfusion Parameters
                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Mismatch Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                      2. Advanced Imaging
                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Vessel Wall Imaging
                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Susceptibility-Weighted Imaging
                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Arterial Spin Labeling
                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Laboratory Studies
                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Routine Laboratory Tests
                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Complete Blood Count
                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Basic Metabolic Panel
                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Liver Function Tests
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Lipid Profile
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Coagulation Studies
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. PT/INR
                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. aPTT
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Platelet Function
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Cardiac Biomarkers
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Troponin
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. BNP/NT-proBNP
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Inflammatory Markers
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. ESR
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. CRP
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Specialized Tests
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Hypercoagulable Workup
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Vasculitis Markers
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Genetic Testing
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      2. Cardiac Evaluation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Electrocardiography
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Rhythm Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Ischemic Changes
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Conduction Abnormalities
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Cardiac Monitoring
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Telemetry
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Holter Monitoring
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Event Monitors
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Echocardiography
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Transthoracic Echo
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Transesophageal Echo
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Bubble Study
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Advanced Cardiac Imaging
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Cardiac MRI
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Cardiac CT
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            2. Vascular Studies
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Carotid Ultrasound
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Stenosis Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Plaque Characterization
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Transcranial Doppler
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Intracranial Stenosis
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Emboli Detection
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Vasospasm Monitoring
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Acute Stroke Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Prehospital Care
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Stroke Recognition
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. FAST Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. EMS Protocols
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            2. Transport Decisions
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Stroke Center Selection
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Time Considerations
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Emergency Department Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Triage and Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Door-to-Needle Times
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Rapid Evaluation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Initial Stabilization
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Airway Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Blood Pressure Control
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Glucose Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Temperature Control
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Acute Ischemic Stroke Treatment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Intravenous Thrombolysis
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Alteplase Administration
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Inclusion Criteria
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Exclusion Criteria
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Dosing and Monitoring
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Complications Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Symptomatic ICH
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Angioedema
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Systemic Bleeding
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Mechanical Thrombectomy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Patient Selection
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Large Vessel Occlusion
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Time Windows
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Imaging Criteria
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Procedural Techniques
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Stent Retrievers
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Aspiration Devices
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Combined Approaches
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        2. Anesthesia Considerations
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Post-Procedure Care
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Antiplatelet Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Aspirin
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Timing and Dosing
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Contraindications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                2. Dual Antiplatelet Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. High-Risk TIA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Minor Stroke
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Anticoagulation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Acute Indications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Timing Considerations
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Monitoring Requirements
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      2. Acute Hemorrhagic Stroke Treatment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Blood Pressure Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Target Blood Pressures
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Antihypertensive Agents
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Monitoring Requirements
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Reversal of Anticoagulation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Warfarin Reversal
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Vitamin K
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Prothrombin Complex Concentrate
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Fresh Frozen Plasma
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      2. DOAC Reversal
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Specific Antidotes
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. General Measures
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Antiplatelet Reversal
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Platelet Transfusion
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Desmopressin
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            2. Surgical Interventions
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Hematoma Evacuation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Indications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Surgical Techniques
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Minimally Invasive Approaches
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Decompressive Craniectomy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Indications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Timing
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Complications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Aneurysm Treatment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Surgical Clipping
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Endovascular Coiling
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Flow Diverters
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                2. Ventriculostomy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. ICP Monitoring
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. CSF Drainage
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                3. General Supportive Care
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Neurological Monitoring
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Neurological Checks
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. ICP Monitoring
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Seizure Monitoring
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        2. Medical Complications Prevention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Deep Vein Thrombosis
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Prophylaxis Methods
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Risk Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Pneumonia Prevention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Aspiration Precautions
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Early Mobilization
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Pressure Ulcer Prevention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Positioning
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Skin Care
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Nutritional Support
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Swallowing Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Feeding Methods
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Nutritional Requirements
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Bladder and Bowel Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Catheter Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Bowel Programs
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          3. Stroke Complications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Neurological Complications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Cerebral Edema
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Pathophysiology
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Monitoring
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Hemorrhagic Transformation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Risk Factors
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Classification
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Seizures
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Incidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Risk Factors
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Treatment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                2. Hydrocephalus
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Mechanisms
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Treatment Options
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Medical Complications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Cardiac Complications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Arrhythmias
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Myocardial Infarction
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Heart Failure
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Pulmonary Complications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Pneumonia
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Pulmonary Embolism
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Respiratory Failure
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                2. Gastrointestinal Complications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Stress Ulcers
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Gastrointestinal Bleeding
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Ileus
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      2. Genitourinary Complications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Urinary Tract Infections
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Urinary Retention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Incontinence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            2. Metabolic Complications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Hyperglycemia
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Hyponatremia
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Malnutrition
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Stroke Recovery and Rehabilitation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Neuroplasticity Principles
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Mechanisms of Recovery
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Diaschisis Resolution
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Collateral Sprouting
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Synaptic Plasticity
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Neurogenesis
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Factors Affecting Recovery
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Age
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Lesion Size and Location
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Comorbidities
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Rehabilitation Intensity
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Critical Periods
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Acute Phase
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Subacute Phase
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Chronic Phase
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      2. Rehabilitation Team
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Physiatrist
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Medical Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Rehabilitation Planning
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            2. Physical Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Mobility Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Gait Training
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Strength Training
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Balance Training
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Occupational Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Activities of Daily Living
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Cognitive Rehabilitation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Adaptive Equipment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Home Safety
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            2. Speech-Language Pathology
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Aphasia Treatment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Dysarthria Treatment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Swallowing Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Cognitive-Communication
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Neuropsychology
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Cognitive Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Cognitive Rehabilitation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Behavioral Interventions
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Social Work
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Discharge Planning
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Resource Coordination
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Family Support
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Rehabilitation Settings
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Acute Rehabilitation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Inpatient Rehabilitation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Admission Criteria
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Length of Stay
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      2. Subacute Rehabilitation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Skilled Nursing Facilities
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Long-Term Care
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2. Outpatient Rehabilitation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Outpatient Clinics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Home Health
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Community Programs
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Specific Impairment Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Motor Recovery
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Hemiparesis Treatment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Spasticity Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Constraint-Induced Movement Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Robotic Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        2. Language Recovery
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Aphasia Types and Treatment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Alternative Communication
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Technology-Assisted Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Cognitive Recovery
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Attention Training
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Memory Strategies
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Executive Function Training
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Swallowing Recovery
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Dysphagia Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Swallowing Strategies
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Diet Modifications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        2. Long-Term Outcomes
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Functional Outcomes
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Independence Measures
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Quality of Life
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Return to Work
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Vocational Rehabilitation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Workplace Modifications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Driving Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Cognitive Requirements
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Physical Requirements
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Adaptive Equipment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Secondary Stroke Prevention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Risk Factor Modification
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Blood Pressure Control
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Target Blood Pressures
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Antihypertensive Medications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Lifestyle Modifications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Lipid Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Statin Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. LDL Targets
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Non-Statin Therapies
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    2. Diabetes Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Glycemic Control
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Cardiovascular Risk Reduction
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        2. Smoking Cessation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Counseling
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Pharmacotherapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Support Programs
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              2. Weight Management
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Diet Modifications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Exercise Programs
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Bariatric Surgery
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Antithrombotic Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Antiplatelet Agents
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Aspirin
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Clopidogrel
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Dipyridamole
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Dual Antiplatelet Therapy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            2. Anticoagulation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Atrial Fibrillation
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Other Indications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Bleeding Risk Assessment
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Monitoring Requirements
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Surgical Interventions
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Carotid Endarterectomy
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Indications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Surgical Technique
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1. Complications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1. Outcomes
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            2. Carotid Artery Stenting
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1. Patient Selection
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1. Procedural Considerations
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  1. Comparison with CEA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  2. Intracranial Stenting
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1. Indications
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1. Outcomes
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1. Complications