Reproductive Biology

  1. Fertilization and Early Development
    1. Gamete Transport and Preparation
      1. Sperm Transport
        1. Journey Through Female Tract
          1. Cervical Mucus Penetration
            1. Uterine Contractions
              1. Fallopian Tube Transport
              2. Sperm Capacitation
                1. Biochemical Changes
                  1. Membrane Modifications
                    1. Hyperactivation
                      1. Timing and Location
                      2. Ovum Transport
                        1. Ovulation Process
                          1. Fimbrial Pickup
                            1. Ciliary Transport
                              1. Timing Considerations
                            2. Fertilization Process
                              1. Sperm-Egg Recognition
                                1. Zona Pellucida Binding
                                  1. Species Specificity
                                    1. ZP3 Receptor Interaction
                                    2. Acrosome Reaction
                                      1. Trigger Mechanisms
                                        1. Enzymatic Release
                                          1. Zona Pellucida Penetration
                                          2. Sperm-Egg Membrane Fusion
                                            1. Membrane Recognition
                                              1. Fusion Mechanisms
                                                1. Sperm Entry
                                                2. Cortical Reaction
                                                  1. Cortical Granule Release
                                                    1. Zona Pellucida Modification
                                                      1. Block to Polyspermy
                                                      2. Pronuclear Formation and Fusion
                                                        1. Male Pronucleus Formation
                                                          1. Female Pronucleus Formation
                                                            1. DNA Replication
                                                              1. Pronuclear Fusion
                                                                1. Zygote Formation
                                                              2. Early Embryonic Development
                                                                1. Cleavage
                                                                  1. First Cleavage Division
                                                                    1. Subsequent Divisions
                                                                      1. Cell Size Reduction
                                                                        1. Totipotency
                                                                        2. Morula Formation
                                                                          1. Compaction Process
                                                                            1. Cell-Cell Adhesion
                                                                              1. Inside-Outside Positioning
                                                                              2. Blastocyst Formation
                                                                                1. Blastocoel Formation
                                                                                  1. Trophoblast Development
                                                                                    1. Inner Cell Mass Formation
                                                                                      1. Hatching from Zona Pellucida
                                                                                      2. Implantation
                                                                                        1. Blastocyst Attachment
                                                                                          1. Trophoblast Invasion
                                                                                            1. Endometrial Response
                                                                                              1. Maternal-Fetal Interface Establishment

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                                                                                          4. Human Reproductive Anatomy and Physiology

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                                                                                          6. Pregnancy and Fetal Development