Metabolic Engineering

  1. Advanced and Emerging Topics
    1. Systems Biology Integration
      1. Multi-Scale Modeling
        1. Data Integration Approaches
          1. Network Analysis Tools
            1. Predictive Modeling
            2. Synthetic Biology Tools
              1. Genetic Circuits
                1. Toggle Switches
                  1. Oscillators
                    1. Logic Gates
                    2. Biosensors
                      1. Transcription Factor-Based
                        1. Riboswitch-Based
                          1. Protein-Based
                          2. Orthogonal Systems
                            1. Orthogonal Ribosomes
                              1. Orthogonal tRNAs
                                1. Minimal Crosstalk
                              2. Computational Design
                                1. Retrosynthesis Algorithms
                                  1. Pathway Prediction
                                    1. Route Optimization
                                      1. Automated Design
                                      2. Machine Learning Applications
                                        1. Strain Design Prediction
                                          1. Pathway Optimization
                                            1. Data-Driven Modeling
                                            2. Laboratory Automation
                                              1. Robotic Strain Construction
                                                1. High-Throughput Experimentation
                                                  1. Automated Analytics
                                                2. Compartmentalization Strategies
                                                  1. Subcellular Targeting
                                                    1. Mitochondrial Engineering
                                                      1. Chloroplast Engineering
                                                        1. Peroxisomal Pathways
                                                        2. Bacterial Microcompartments
                                                          1. Protein Shell Engineering
                                                            1. Metabolic Channeling
                                                              1. Synthetic Compartments
                                                              2. Artificial Organelles
                                                                1. Synthetic Vesicles
                                                                  1. Protein-Based Compartments
                                                                2. Regulatory and Ethical Considerations
                                                                  1. GMO Regulations
                                                                    1. Regulatory Frameworks
                                                                      1. Safety Assessment
                                                                        1. Environmental Release
                                                                        2. Biosafety Measures
                                                                          1. Containment Strategies
                                                                            1. Kill Switches
                                                                              1. Risk Assessment
                                                                              2. Public Acceptance
                                                                                1. Communication Strategies
                                                                                  1. Ethical Considerations
                                                                                  2. Commercialization Challenges
                                                                                    1. Scale-Up Issues
                                                                                      1. Economic Viability
                                                                                        1. Technology Transfer