Gene Editing

  1. Future Directions and Emerging Technologies
    1. Technical Improvements
      1. Enhanced Specificity
        1. High-Fidelity Nucleases
          1. Improved Guide RNA Design
            1. Machine Learning Applications
            2. Increased Efficiency
              1. Optimized Delivery Systems
                1. Enhanced Repair Pathways
                  1. Multiplexed Editing
                  2. Expanded Targeting Range
                    1. New PAM Requirements
                      1. Epigenome Editing
                        1. RNA Editing Capabilities
                      2. Advanced Delivery Systems
                        1. Targeted Delivery
                          1. Cell-type Specific Vectors
                            1. Tissue-specific Promoters
                              1. Ligand-directed Targeting
                              2. Improved Delivery Vehicles
                                1. Next-generation Viral Vectors
                                  1. Synthetic Delivery Systems
                                    1. Biomimetic Approaches
                                    2. Non-invasive Delivery
                                      1. Oral Delivery Systems
                                        1. Transdermal Delivery
                                          1. Inhalation-based Delivery
                                        2. Integration with Other Technologies
                                          1. Synthetic Biology
                                            1. Biological Circuit Design
                                              1. Programmable Cellular Functions
                                                1. Biosensor Integration
                                                2. Artificial Intelligence
                                                  1. Predictive Modeling
                                                    1. Automated Design
                                                      1. Data Analysis
                                                      2. Regenerative Medicine
                                                        1. Stem Cell Engineering
                                                          1. Tissue Engineering
                                                            1. Organoid Development
                                                            2. Precision Medicine
                                                              1. Personalized Therapies
                                                                1. Biomarker-guided Treatment
                                                                  1. Companion Diagnostics
                                                                2. Emerging Applications
                                                                  1. Complex Genetic Disorders
                                                                    1. Polygenic Diseases
                                                                      1. Multifactorial Conditions
                                                                        1. Psychiatric Disorders
                                                                        2. Aging and Longevity
                                                                          1. Cellular Senescence
                                                                            1. Lifespan Extension
                                                                            2. Space Medicine
                                                                              1. Radiation Protection
                                                                                1. Adaptation to Space Environment
                                                                                2. Pandemic Preparedness
                                                                                  1. Rapid Vaccine Development
                                                                                    1. Antiviral Strategies
                                                                                      1. Diagnostic Tools

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                                                                                  13. Regulation and Governance

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                                                                                  1. Foundational Concepts in Genetics