Developmental Biology

  1. Gametogenesis and Fertilization
    1. Germ Line Establishment
      1. Germ Cell Specification
        1. Primordial Germ Cells
          1. Origin and Specification
            1. Molecular Markers
              1. Transcriptional Control
              2. Germ Cell Migration
                1. Migration Pathways
                  1. Guidance Molecules
                    1. Gonad Colonization
                    2. Germ Cell Niche
                      1. Niche Components
                        1. Maintenance Signals
                          1. Stem Cell Regulation
                        2. Spermatogenesis
                          1. Overview and Stages
                            1. Mitotic Phase
                              1. Spermatogonial Stem Cells
                                1. Amplifying Divisions
                                2. Meiotic Phase
                                  1. Meiosis I
                                    1. Meiosis II
                                      1. Genetic Recombination
                                      2. Differentiation Phase
                                        1. Spermiogenesis
                                          1. Morphological Changes
                                            1. Chromatin Condensation
                                            2. Sperm Structure
                                              1. Head Region
                                                1. Acrosome
                                                  1. Midpiece
                                                    1. Flagellum
                                                    2. Hormonal Regulation
                                                      1. FSH and LH
                                                        1. Testosterone
                                                          1. Local Factors
                                                        2. Oogenesis
                                                          1. Overview and Stages
                                                            1. Mitotic Phase
                                                              1. Oogonial Proliferation
                                                              2. Meiotic Phase
                                                                1. Meiosis I Arrest
                                                                  1. Meiosis II Completion
                                                                    1. Asymmetrical Division
                                                                    2. Oocyte Maturation
                                                                      1. Nuclear Maturation
                                                                        1. Cytoplasmic Maturation
                                                                          1. Hormonal Triggers
                                                                          2. Egg Structure
                                                                            1. Yolk Components
                                                                              1. Yolk Distribution Patterns
                                                                                1. Cortical Granules
                                                                                  1. Protective Coats
                                                                                    1. Vitelline Envelope
                                                                                      1. Zona Pellucida
                                                                                      2. Maternal Factors
                                                                                        1. mRNA Storage
                                                                                          1. Protein Accumulation
                                                                                            1. Organelle Distribution
                                                                                          2. Fertilization Process
                                                                                            1. Sperm Capacitation
                                                                                              1. Biochemical Changes
                                                                                                1. Membrane Modifications
                                                                                                2. Species Recognition
                                                                                                  1. Binding Proteins
                                                                                                    1. Species Specificity
                                                                                                      1. Recognition Mechanisms
                                                                                                      2. Sperm-Egg Interaction
                                                                                                        1. Initial Binding
                                                                                                          1. Acrosome Reaction
                                                                                                            1. Membrane Fusion
                                                                                                            2. Polyspermy Prevention
                                                                                                              1. Fast Block
                                                                                                                1. Membrane Depolarization
                                                                                                                  1. Slow Block
                                                                                                                    1. Cortical Granule Reaction
                                                                                                                    2. Egg Activation
                                                                                                                      1. Calcium Signaling
                                                                                                                        1. Metabolic Activation
                                                                                                                          1. Cell Cycle Resumption
                                                                                                                          2. Nuclear Events
                                                                                                                            1. Pronuclear Formation
                                                                                                                              1. Pronuclear Migration
                                                                                                                                1. Syngamy
                                                                                                                                  1. First Mitosis

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                                                                                                                              1. Introduction to Developmental Biology

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                                                                                                                              3. Early Embryonic Development