Developmental Biology

  1. Developmental Biology in Context
    1. Evolutionary Developmental Biology
      1. Deep Homology
        1. Conserved Developmental Genes
          1. Toolkit Genes
            1. Regulatory Networks
            2. Developmental Constraints
              1. Phylogenetic Constraints
                1. Functional Constraints
                  1. Structural Constraints
                  2. Evolutionary Mechanisms
                    1. Gene Duplication
                      1. Regulatory Evolution
                        1. Heterochrony
                          1. Heterotopy
                          2. Novel Structure Evolution
                            1. Co-option
                              1. Modularity
                                1. Developmental Systems Drift
                              2. Ecological Developmental Biology
                                1. Environmental Influences
                                  1. Temperature Effects
                                    1. Nutritional Effects
                                      1. Chemical Signals
                                        1. Physical Forces
                                        2. Developmental Plasticity
                                          1. Phenotypic Plasticity
                                            1. Polyphenism
                                              1. Reaction Norms
                                                1. Adaptive Plasticity
                                                2. Teratogenesis
                                                  1. Teratogen Types
                                                    1. Critical Periods
                                                      1. Dose-Response Relationships
                                                        1. Mechanisms of Action
                                                      2. Medical Applications
                                                        1. Birth Defects
                                                          1. Genetic Causes
                                                            1. Environmental Causes
                                                              1. Multifactorial Causes
                                                                1. Prevention Strategies
                                                                2. Prenatal Diagnosis
                                                                  1. Screening Methods
                                                                    1. Diagnostic Techniques
                                                                      1. Genetic Counseling
                                                                      2. Reproductive Technologies
                                                                        1. In Vitro Fertilization
                                                                          1. Embryo Selection
                                                                            1. Genetic Testing
                                                                          2. Cancer and Development
                                                                            1. Developmental Parallels
                                                                              1. Growth Control
                                                                                1. Cell Migration
                                                                                  1. Differentiation Block
                                                                                  2. Oncogenes in Development
                                                                                    1. Growth Factor Signaling
                                                                                      1. Transcription Factors
                                                                                        1. Cell Cycle Regulators
                                                                                        2. Tumor Suppressor Genes
                                                                                          1. p53 Pathway
                                                                                            1. Rb Pathway
                                                                                              1. Developmental Roles
                                                                                              2. Cancer Stem Cells
                                                                                                1. Stem Cell Properties
                                                                                                  1. Therapeutic Targets
                                                                                                    1. Resistance Mechanisms