Embryology

  1. Third Week of Development
    1. Gastrulation
      1. Initiation of Gastrulation
        1. The Primitive Streak
          1. Formation and Location
            1. Primitive Node
              1. Primitive Pit
                1. Primitive Groove
                2. Ingression of Epiblast Cells
                  1. Formation of the Three Primary Germ Layers
                    1. Endoderm
                      1. Mesoderm
                        1. Ectoderm
                        2. Fate Mapping of Germ Layers
                        3. Notochord Formation
                          1. Notochordal Process
                            1. Notochordal Canal
                              1. Notochordal Plate
                                1. Definitive Notochord
                                  1. Role in Induction
                                  2. Neurulation
                                    1. Induction by the Notochord
                                      1. Neural Plate
                                        1. Neural Folds and Neural Groove
                                          1. Fusion of Neural Folds
                                            1. Neural Tube Formation
                                              1. Closure of Anterior Neuropore
                                                1. Closure of Posterior Neuropore
                                                  1. Neural Tube Defects
                                                  2. Neural Crest Cells
                                                    1. Formation and Migration
                                                      1. Major Derivatives
                                                        1. Peripheral Nervous System
                                                          1. Melanocytes
                                                            1. Craniofacial Structures
                                                              1. Adrenal Medulla
                                                            2. Differentiation of the Mesoderm
                                                              1. Paraxial Mesoderm
                                                                1. Somites
                                                                  1. Formation and Segmentation
                                                                    1. Sclerotome
                                                                      1. Myotome
                                                                        1. Dermatome
                                                                      2. Intermediate Mesoderm
                                                                        1. Urogenital Structures
                                                                        2. Lateral Plate Mesoderm
                                                                          1. Somatic Mesoderm
                                                                            1. Splanchnic Mesoderm
                                                                              1. Intraembryonic Coelom
                                                                            2. Early Cardiovascular System Development
                                                                              1. Vasculogenesis
                                                                                1. Angiogenesis
                                                                                  1. Formation of Blood Islands
                                                                                    1. Formation of the Primitive Heart Tube
                                                                                      1. Early Circulatory Patterns

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                                                                                    4. Second Week of Development

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                                                                                    6. Fourth to Eighth Week