Metabolism

  1. Enzymes and Coenzymes in Metabolism
    1. Enzyme Function and Catalysis
      1. Mechanism of Enzyme Action
        1. Active Site Structure
          1. Substrate Specificity
            1. Transition State Stabilization
              1. Induced Fit Model
              2. Enzyme Kinetics
                1. Michaelis-Menten Kinetics
                  1. Vmax Determination
                    1. Km Significance
                      1. Lineweaver-Burk Plot
                        1. Factors Affecting Enzyme Activity
                        2. Enzyme Regulation
                          1. Allosteric Regulation
                            1. Positive Effectors
                              1. Negative Effectors
                                1. Conformational Changes
                                2. Covalent Modification
                                  1. Phosphorylation
                                    1. Methylation
                                      1. Acetylation
                                      2. Feedback Inhibition
                                        1. End-Product Inhibition
                                          1. Metabolic Control
                                          2. Competitive Inhibition
                                            1. Non-competitive Inhibition
                                              1. Enzyme Induction and Repression
                                                1. Isoenzymes
                                                2. Key Coenzymes and Electron Carriers
                                                  1. NAD+ and NADH
                                                    1. Structure
                                                      1. Function in Redox Reactions
                                                        1. Metabolic Roles
                                                        2. FAD and FADH2
                                                          1. Structure
                                                            1. Function in Redox Reactions
                                                              1. Metabolic Roles
                                                              2. Coenzyme A
                                                                1. Structure
                                                                  1. Acyl Group Transfer
                                                                    1. Metabolic Significance
                                                                    2. Thiamine Pyrophosphate
                                                                      1. Biotin
                                                                        1. Lipoic Acid
                                                                          1. Pyridoxal Phosphate
                                                                            1. Folate Coenzymes

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                                                                          3. The Role of ATP in Metabolism

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                                                                          5. Carbohydrate Metabolism